RANBP1 antibody (C-Term)

Catalog No. ABIN630712

This Rabbit Polyclonal antibody specifically detects RANBP1 in WB. It exhibits reactivity toward Human.

Quick Overview for RANBP1 antibody (C-Term) (ABIN630712)

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RANBP1 Antibody

Binding Specificity: C-Term

Specificity: RanBP1 antibody was raised against the C terminal of RANBP1

Purification: Affinity purified

Immunogen: RanBP1 antibody was raised using the C terminal of RANBP1 corresponding to a region with amino acids KFEECRKEIEEREKKAGSGKNDHAEKVAEKLEALSVKEETKEDAEEKQ

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RanBP1 Blocking Peptide, (ABIN939753), is also available for use as a blocking control in assays to test for specificity of this RanBP1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RANBP1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for RANBP1

Target: RANBP1 (RAN Binding Protein 1 (RANBP1))

Alternative Name: RanBP1

Background: Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN. RANBP1 encodes a 23 kDa protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.

Molecular Weight: 23 kDa (MW of target protein)