TMOD3 antibody

Catalog No. ABIN632192

The Rabbit Polyclonal anti-TMOD3 antibody is suitable to detect TMOD3 in samples from Human. It has been validated for WB.

Quick Overview for TMOD3 antibody (ABIN632192)

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMOD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TMOD3 Antibody

Purification: Affinity purified

Immunogen: Tropomodulin 3 antibody was raised using a synthetic peptide corresponding to a region with amino acids LDDLDPENALLPAGFRQKNQTSKSTTGPFDREHLLSYLEKEALEHKDRED

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

Tropomodulin 3 Blocking Peptide, (ABIN940225), is also available for use as a blocking control in assays to test for specificity of this Tropomodulin 3 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TMOD3 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for TMOD3

Target: TMOD3 (Tropomodulin 3 (TMOD3))

Alternative Name: Tropomodulin 3

Background: TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.

Molecular Weight: 39 kDa (MW of target protein)

Pathways: Regulation of Actin Filament Polymerization