PCDHB15 antibody (N-Term)

Catalog No. ABIN633068

The Rabbit Polyclonal anti-PCDHB15 antibody is suitable to detect PCDHB15 in samples from Human. It has been validated for WB.

Quick Overview for PCDHB15 antibody (N-Term) (ABIN633068)

Target: PCDHB15 (Protocadherin beta 15 (PCDHB15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHB15 Antibody

Binding Specificity: N-Term

Specificity: PCDHB15 antibody was raised against the N terminal of PCDHB15

Purification: Affinity purified

Immunogen: PCDHB15 antibody was raised using the N terminal of PCDHB15 corresponding to a region with amino acids VMEETERGSFVANLANDLGLGVGELAERGARVVSEDNEQGLQLDLQTGQL

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

PCDHB15 Blocking Peptide, (ABIN5615251), is also available for use as a blocking control in assays to test for specificity of this PCDHB15 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PCDHB15 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for PCDHB15

Target: PCDHB15 (Protocadherin beta 15 (PCDHB15))

Alternative Name: PCDHB15

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Molecular Weight: 83 kDa (MW of target protein)