CD137 antibody

Catalog No. ABIN636609

The Goat Polyclonal anti-CD137 antibody (ABIN636609) specifically detects CD137 in ELISA, WB and InhibAb. The antibody is reactive with Human samples.

Quick Overview for CD137 antibody (ABIN636609)

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CD137 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Blocking Antibody (InhibAb)

Product Details anti-CD137 Antibody

Purification: Purified

Immunogen: CD137 antibody was raised in goat using highly pure recombinant human 4-1 BB receptor as the immunogen.

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for CD137

Target: CD137 (TNFRSF9) (Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))

Alternative Name: CD137

Background: CD137 or 4-1BB Receptor, a member of the TNF superfamily of receptors, is mainly expressed on the surface of a variety of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB Receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB Receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB Receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain.

Molecular Weight: 17.7 kDa (predicted detection band MW)

Pathways: Cancer Immune Checkpoints