MC4R antibody

Catalog No. ABIN636766

This Rabbit Polyclonal antibody specifically detects MC4R . It exhibits reactivity toward Human.

Quick Overview for MC4R antibody (ABIN636766)

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MC4R antibody is un-conjugated

Application: Please inquire

Product Details anti-MC4R Antibody

Cross-Reactivity (Details): This 14 AA human MCR42 immunogenic peptide sequence is 100 % identical in monkey, pig, & bovine, 84 % with mouse, and 69 % homologous with rat MC4-R. No significant sequence homology of MCR42 is seen with other melanocortin receptors.

Purification: Affinity chromatography purified

Immunogen: MC4 R antibody was raised in rabbit using a 14 amino acid peptide of human MC4-R as the immunogen.

Isotype: IgG

Application Details

Application Notes: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Supplied in 100 mM Tris, pH 7.5, with 0.2 % BSA and 0.05 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for MC4R

Target: MC4R (Melanocortin 4 Receptor (MC4R))

Alternative Name: MC4R

Background: Melanocortin receptor 4 is a protein that in humans is encoded by the MC4R gene. It encodes the MC4 protein, a G-protein coupled receptor that binds alpha-melanocyte stimulating hormone ( alpha-MSH). In murine models MC4 receptors have been found to be involved in feeding behaviour, the regulation of metabolism, sexual behaviour, and male erectile function.

Pathways: Hormone Transport, cAMP Metabolic Process, Feeding Behaviour