TNF alpha antibody (Biotin)
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- Target See all TNF alpha Antibodies
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
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Reactivity
- Cow
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNF alpha antibody is conjugated to Biotin
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- Mouse Anti-Bovine TNF-alpha [+Biotin]
- Specificity
- This product recognizes bovine TNF alpha, a 17.5kDa cytokine, expressed by many different stimulated cell types including monocytes, macrophages, endothelial cells, fibroblasts and both T and B-lymphocytes. The production of TNF alpha is induced by a variety of factors, dependant upon cell type and includes bacterial toxins, IL-1, PDGF, IFN-beta, NGF, Oncostatin M and viral infections. The presence of TNF alpha is responsible for diverse immunomodulatory, anti-tumour and toxic effects and under certain conditions is also capable of self-stimulation and inhibition. This biotin conjugate may be used as a detection antibody in ELISA assays for bovine TNF alpha in combination with DS-MB-02436 as capture reagent.
- Cross-Reactivity
- Sheep (Ovine)
- Characteristics
- Cytokines/Chemokines/Growth Factors/Receptors
- Immunogen
- Recombinant bovine TNF alpha
- Isotype
- IgG2a
- Top Product
- Discover our top product TNF alpha Primary Antibody
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- Application Notes
- ELISA (dilution: 1/10 , 1/100), Flow Cytometry
- Restrictions
- For Research Use only
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- Concentration
- IgG concentration 1.0 mg/ml
- Buffer
- Phosphate buffered saline pH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C
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- Target
- TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
- Alternative Name
- Tumor Necrosis Factor alpha (TNF-alpha) (TNF alpha Products)
- Pathways
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome
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