IL-6 Receptor antibody

Catalog No. ABIN639299

Product Details anti-IL-6 Receptor Antibody

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-6 Receptor antibody is un-conjugated

Application: Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Purpose: Mouse Anti-Human CD126

Specificity: This antibody recognizes soluble and membranous human IL-6R. This antibody has been shown to inhibit IL-6 mediated proliferation of XG-1 cells, and partially blocks binding of IL-6 to its receptor. Removal of Sodium azide is recommended prior to use in functional assays Flow Cytometry: Use 10ul of the suggested working dilution to label 10 6 cells in 100ul

Characteristics: Adhesion Molecule/Cell Surface

Purification: Purified

Immunogen: CHO cells transfected with cDNA of the IL-6 receptor

Isotype: IgG1

Application Details

Application Notes: Immunohistology - Frozen, ELISA (dilution: , 1/50), Flow Cytometry, Immunofluorescence, Immunoprecipitation

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Alternative Name: CD126 (IL-6R) (IL6R Products)

Pathways: JAK-STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints