Complement C3b antibody

Catalog No. ABIN644662

This Mouse Monoclonal antibody specifically detects Complement C3b in WB and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for Complement C3b antibody (ABIN644662)

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Complement C3b antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Complement C3b Antibody

Purpose: Mouse Anti-Human C3b

Specificity: This product is specific for C3b, part of the complement system. C3 is cleaved by C3-convertase creating C3a and C3b, which binds to the surface of pathogens leading to their destruction by phagocytic cells. This antibody recognizes a determinant present on native (circulating) C3 and on the fragments C3b and C3c. The antibody is directed to a determinant present on the betachain of the C3 molecule (Western blot). It does not react with the anaphylatoxin C3a or the fragment C3d and does not inhibit the haemolytic function of C3.

Characteristics: Blood Coagulation Proteins

Purification: Purified

Immunogen: Human C3b

Isotype: IgG1

Application Details

Application Notes: Immunohistology - Frozen, Western Blotting

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute with 1.0 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommend that the vial is gently mixed after reconstitution.

Concentration: IgG concentration 50 ug/ml after reconstitution

Buffer: Phosphate buffered saline

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for Complement C3b

Target: Complement C3b (C3b) (Complement C3 beta Chain (C3b))

Alternative Name: C3b

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling