Retinoid X Receptor beta antibody

Catalog No. ABIN645872

The Goat not_set anti-Retinoid X Receptor beta antibody is suitable to detect Retinoid X Receptor beta in samples from Human, Mouse and Rat.

Quick Overview for Retinoid X Receptor beta antibody (ABIN645872)

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivity: Human, Mouse, Rat

Host: Goat

Conjugate: This Retinoid X Receptor beta antibody is un-conjugated

Application: Please inquire

Product Details anti-Retinoid X Receptor beta Antibody

Specificity: The Goat anti-RXR beta antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Characteristics: Goat Anti-RXR beta

Immunogen: Peptide with sequence CRDGMGDSGRDSRSP, from the internal region of the protein sequence according to NP_068811, was used as an immunogen.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Storage: -20 °C

Target Details for Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Alternative Name: RXR beta

Background: Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins that exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

NCBI Accession: NP_068811

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway