This Transferrin Receptor antibody is conjugated to FITC
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC)
Specificity
DF1513, produces mouse IgG1 immunoglobulins directed against the transferrin receptor. The transferrin receptor is a type II membrane glycoprotein existing as a homodimer of 180-190 kD with the interchain disulphide bond
Antigen distribution: Expression of CD71, or the transferrin receptor, is very low on resting leukocytes but is upregulated upon activation reflecting the iron dependence of activation. In other tissues, CD71 is expressed on most dividing cells and also on brain endothelium and alveolar macrophage [1,2]. The ligand is the serum iron transport protein transferrin. DF1513 was clustered at the Leukocyte Typing Workshop IV [5]. Cellular Expression: Activated leukocytes.