You are viewing an incomplete version of our website. Please click to reload the website as full version.

GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) antibody

Details for Product No. ABIN650659, Supplier: Log in to see
Antigen
  • GABARAPL2
  • atg8
  • gef2
  • gate16
  • gate-16
  • Gef2
  • ATG8
  • ATG8C
  • GATE-16
  • GATE16
  • GEF-2
  • GEF2
  • zgc:92319
  • 0610012F20Rik
  • 2900019O08Rik
  • AI173605
Reactivity
Human
161
33
32
2
1
1
1
1
Host
Rabbit
157
3
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
21
21
21
10
10
10
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
115
95
78
15
11
6
6
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This GABARAPL2 antibody is generated from rabbits immunized with human GABARAPL2 recombinant protein.
Clone RB22734
Isotype Ig
Specificity This GABARAPL2 antibody is generated from rabbits immunized with human GABARAPL2 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GABARAPL2 (GABARAPL2 Antibody Abstract)
Background Membrane proteins located on vesicles (v-SNAREs) and on the target membrane (t-SNAREs) mediate specific recognition and, possibly, fusion between a transport vesicle and its target membrane. The activity of SNARE molecules is regulated by several soluble cytosolic proteins. We have cloned a bovine brain cDNA encoding a conserved 117 amino acid polypeptide, denoted Golgi-associated ATPase Enhancer of 16 kDa (GATE-16), that functions as a soluble transport factor. GATE-16 interacts with N-ethylmaleimidesensitive factor (NSF) and significantly stimulates its ATPase activity. It also interacts with the Golgi v-SNARE GOS-28 in an NSF-dependent manner. We propose that GATE-16 modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation.
Synonyms: GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, MAP1 light chain 3-related protein
Molecular Weight 13536 DA
Gene ID 11345
UniProt P60520
Research Area Autophagy
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) antibody (ABIN650659) Western blot analysis of GABARAPL2 Antibody (ABIN650659) in MCF-7 cell line lysates (...
Immunohistochemistry (IHC) image for anti-GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) antibody (ABIN650659) Formalin-fixed and paraffin-embedded mouse brain tissue reacted with GABARAPL2 Antibo...
Flow Cytometry (FACS) image for anti-GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) antibody (ABIN650659) GABARAPL2 Antibody (ABIN650659) FC analysis of MCF-7 cells (bottom histogram) compare...
Background publications Sou, Tanida, Komatsu et al.: "Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16." in: The Journal of biological chemistry, Vol. 281, Issue 6, pp. 3017-24, 2006 (PubMed).

Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).