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Details for Product No. ABIN650659

GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) antibody

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Antigen
Synonyms ATG8, ATG8C, GATE-16, GATE16, GEF-2, GEF2, Gef2, 0610012F20Rik, 2900019O08Rik, AI173605, zgc:92319, atg8, gate-16, gate16, gef2, GABARAPL2
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN650659
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This GABARAPL2 antibody is generated from rabbits immunized with human GABARAPL2 recombinant protein.
Clone RB22734
Isotype Ig
Specificity This GABARAPL2 antibody is generated from rabbits immunized with human GABARAPL2 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GABARAPL2
Background Membrane proteins located on vesicles (v-SNAREs) and on the target membrane (t-SNAREs) mediate specific recognition and, possibly, fusion between a transport vesicle and its target membrane. The activity of SNARE molecules is regulated by several soluble cytosolic proteins. We have cloned a bovine brain cDNA encoding a conserved 117 amino acid polypeptide, denoted Golgi-associated ATPase Enhancer of 16 kDa (GATE-16), that functions as a soluble transport factor. GATE-16 interacts with N-ethylmaleimidesensitive factor (NSF) and significantly stimulates its ATPase activity. It also interacts with the Golgi v-SNARE GOS-28 in an NSF-dependent manner. We propose that GATE-16 modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation.
Synonyms: GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, MAP1 light chain 3-related protein
Molecular Weight 13536 DA
Gene ID 11345
UniProt P60520
Research Area Autophagy
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Wiemann, Arlt, Huber et al.: "From ORFeome to biology: a functional genomics pipeline." in: Genome research, Vol. 14, Issue 10B, pp. 2136-44, 2004 (PubMed).

Sou, Tanida, Komatsu et al.: "Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16." in: The Journal of biological chemistry, Vol. 281, Issue 6, pp. 3017-24, 2006 (PubMed).

Alternatives for antigen "GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2)", type "Antibodies"
Hosts (39), (4), (3), (1)
Reactivities (45), (22), (20), (14), (12), (1), (1), (1)
Applications (38), (16), (15), (10), (7), (3), (3), (2), (1)
Conjugates (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (2), (2), (2), (1), (1)
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