Forkhead Box P3 (FOXP3) (pSer418) antibody

Antigen: Forkhead Box P3 (FOXP3)

Synonyms: HNF3A, TCF3A, MGC33105, sf, JM2, scurfin, AIID, IPEX, PIDX, XPID, DIETER, MGC141961, MGC141963, RGD1562112, FOXP3, foxp3

Binding Site: pSer418

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Dot Blot (Dot), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN650867

Additional Information

Alternative name: FOXP3

Gene ID: 50943

UniProt: Q9BZS1, NP_054728

Immunogen: This Phospho-FOXP3-S418 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S418 of human FOXP3.

Isotype: Ig

Description: Other names: Scurfin, Forkhead box protein P3,JM2, IPEX, FOXP3

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This Phospho-FOXP3-S418 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S418 of human FOXP3.

Molecular Weight: 47244  DA

Comments:

Background: The protein is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.

Application Details

Application Notes: ELISA ~~ 1:1,000 Dot blot~~ 1:500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Transcription Factors, Phospho-specific antibodies, Signaling, Cell Structure

Restrictions: For Research Use only

Images

Dot blot analysis of anti-Phospho-FOXP3-S418 Phospho-specific Pab (ABIN650867) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5ug per ml.

Publications

Product: Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).