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Details for Product No. ABIN650868

Lin-28 Homolog A (C. Elegans) (LIN28A) (pSer134) antibody

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Antigen
Synonyms Lin28, csdd1, lin-28, lin28, zcchc1, CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A, AL024421, ENSMUSG00000070700, Gm10299, Lin-28, Tex17, RGD1566408, sb:cb650, zgc:55584
Epitope
»Alternatives pSer134
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunofluorescence (IF), Dot Blot (DB)
Pubmed 3 references available
Catalog no. ABIN650868
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This LIN28 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S134 of human LIN28.
Clone RB18937
Isotype Ig
Specificity This Phospho-LIN28-S134 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S134 of human LIN28.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LIN28
Background LIN28 is probable transcription factor. It plays a critical role in the control of immune response.
Synonyms: Zinc finger CCHC domain-containing protein 1, Protein lin-28 homolog A, Lin-28A,ZCCHC1, LIN28A, CSDD1, LIN28
Molecular Weight 22743ニDa
Gene ID 79727
UniProt Q9H9Z2
Research Area Phospho-specific antibodies, Chromatin, Signaling, Cell Structure
Application Notes Recommend dilutions: IF : 1:100,DB : 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Heo, Joo, Kim et al.: "TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation." in: Cell, Vol. 138, Issue 4, pp. 696-708, 2009 (PubMed).

Iliopoulos, Hirsch, Struhl: "An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation." in: Cell, Vol. 139, Issue 4, pp. 693-706, 2009 (PubMed).

Qiu, Ma, Wang et al.: "Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells." in: Nucleic acids research, Vol. 38, Issue 4, pp. 1240-8, 2010 (PubMed).

Alternatives for antigen "Lin-28 Homolog A (C. Elegans) (LIN28A)", type "Antibodies"
Hosts (46), (20)
Reactivities (63), (32), (22), (14), (14), (2), (1), (1)
Applications (55), (31), (17), (17), (14), (10), (9), (7), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (4), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
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