Lin-28 Homolog A (C. Elegans) (LIN28A) (pSer134) antibody

Details for Product No. ABIN650868
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Antigen
Synonyms Lin28, csdd1, lin-28, lin28, zcchc1, LIN28, CSDD1, LIN-28, ZCCHC1, lin-28A, AL024421, ENSMUSG00000070700, Gm10299, Lin-28, Tex17, RGD1566408, sb:cb650, zgc:55584
Epitope
pSer134
(13), (7), (5), (4), (4), (4), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(81), (30), (21), (13), (13), (1)
Host
Rabbit
(58), (26)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Dot Blot (DB)
(67), (40), (23), (21), (17), (14), (10), (9), (8), (4), (3)
Pubmed 3 references available
Quantity 400 µL
Options
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Catalog No. ABIN650868
291.50 $
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Immunogen This LIN28 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S134 of human LIN28.
Clone RB18937
Isotype Ig
Specificity This Phospho-LIN28-S134 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S134 of human LIN28.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LIN28
Background LIN28 is probable transcription factor. It plays a critical role in the control of immune response.
Synonyms: Zinc finger CCHC domain-containing protein 1, Protein lin-28 homolog A, Lin-28A,ZCCHC1, LIN28A, CSDD1, LIN28
Molecular Weight 22743ニDa
Gene ID 79727
UniProt Q9H9Z2
Research Area Phospho-specific antibodies, Chromatin, Signaling, Cell Structure
Application Notes IF = 1:100, DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (pSer134) antibody Dot blot analysis of anti-Phospho-LIN28-S134 Phospho-specific Pab (ABIN650868) on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL.
Background publications Heo, Joo, Kim et al.: "TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation." in: Cell, Vol. 138, Issue 4, pp. 696-708, 2009 (PubMed).

Iliopoulos, Hirsch, Struhl: "An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation." in: Cell, Vol. 139, Issue 4, pp. 693-706, 2009 (PubMed).

Qiu, Ma, Wang et al.: "Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells." in: Nucleic acids research, Vol. 38, Issue 4, pp. 1240-8, 2010 (PubMed).

Validation Images
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