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Lin-28 Homolog A (C. Elegans) (LIN28A) (pSer134) antibody

Details for Product No. ABIN650868, Supplier: Login to see
Antigen
  • Lin28
  • csdd1
  • lin-28
  • lin28
  • zcchc1
  • LIN28
  • CSDD1
  • LIN-28
  • ZCCHC1
  • lin-28A
  • AL024421
  • ENSMUSG00000070700
  • Gm10299
  • Lin-28
  • Tex17
  • RGD1566408
  • sb:cb650
  • zgc:55584
Epitope
pSer134
15
10
8
7
5
5
5
5
4
3
3
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
140
44
28
1
1
1
Host
Rabbit
110
39
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
4
4
3
3
1
1
1
1
1
1
1
1
1
Application
Dot Blot (DB), Immunofluorescence (IF)
105
58
52
34
24
21
19
18
13
11
7
1
1
1
Supplier
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Immunogen This LIN28 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S134 of human LIN28.
Clone RB18937
Isotype Ig
Specificity This Phospho-LIN28-S134 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S134 of human LIN28.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LIN28 (LIN28A Antibody Abstract)
Background LIN28 is probable transcription factor. It plays a critical role in the control of immune response.
Synonyms: Zinc finger CCHC domain-containing protein 1, Protein lin-28 homolog A, Lin-28A,ZCCHC1, LIN28A, CSDD1, LIN28
Molecular Weight 22743ニDa
Gene ID 79727
UniProt Q9H9Z2
Research Area Phospho-specific antibodies, Chromatin, Signaling, Cell Structure
Pathways
Application Notes IF = 1:100, DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-Lin-28 Homolog A (C. Elegans) (LIN28A) (pSer134) antibody (ABIN650868) Dot blot analysis of anti-Phospho-LIN28-S134 Phospho-specific Pab (ABIN650868) on nit...
Background publications Qiu, Ma, Wang et al.: "Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells." in: Nucleic acids research, Vol. 38, Issue 4, pp. 1240-8, 2010 (PubMed).

Iliopoulos, Hirsch, Struhl: "An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation." in: Cell, Vol. 139, Issue 4, pp. 693-706, 2009 (PubMed).

Heo, Joo, Kim et al.: "TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation." in: Cell, Vol. 138, Issue 4, pp. 696-708, 2009 (PubMed).