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APG8b (MAP1LC3B) (pThr93), (pTyr99) antibody

Details for Product No. ABIN650876, Supplier: Log in to see
Antigen
Epitope
pThr93, pTyr99
1
1
1
1
1
1
Reactivity
Human
3
1
Host
Rabbit
3
Clonality (Clone)
Polyclonal ()
Application
Dot Blot (DB)
2
2
2
1
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Immunogen This APG8b(MAP1LC3B) Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T93/Y99 of human APG8b(MAP1LC3B).
Clone RB17595
Isotype Ig
Specificity This Phospho-APG8b (MAP1LC3B)-T93/Y99 Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding T93/Y99 of human APG8b.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
Synonyms: Microtubule-associated proteins 1A/1B light chain 3B,MAP1LC3B,MAP1ALC3
Molecular Weight 14688 DA
Gene ID 81631
NCBI Accession NP_073729
UniProt Q9GZQ8
Research Area Cell Structure, Autophagy
Pathways
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-APG8b (MAP1LC3B) (pThr93), (pTyr99) antibody (ABIN650876) Dot blot analysis of anti-Phospho-APG8b (MAP1LC3B)-T93/Y99 Phospho-specific Pab (ABIN...
Background publications Kirkin, Lamark, Sou et al.: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).