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Details for Product No. ABIN650876

APG8b (MAP1LC3B) (pThr93), (pTyr99) antibody

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Antigen
Epitope
»Alternatives pThr93, pTyr99
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Dot Blot (DB)
Pubmed 1 reference available
Catalog no. ABIN650876
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This APG8b(MAP1LC3B) Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T93/Y99 of human APG8b(MAP1LC3B).
Clone RB17595
Isotype Ig
Specificity This Phospho-APG8b (MAP1LC3B)-T93/Y99 Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding T93/Y99 of human APG8b.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
Synonyms: Microtubule-associated proteins 1A/1B light chain 3B,MAP1LC3B,MAP1ALC3
Molecular Weight 14688 DA
Gene ID 81631
UniProt NP_073729, Q9GZQ8
Research Area Cell Structure, Autophagy
Application Notes Recommend dilutions: DB : 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Kirkin, Lamark, Sou et al.: "A role for NBR1 in autophagosomal degradation of ubiquitinated substrates." in: Molecular cell, Vol. 33, Issue 4, pp. 505-16, 2009 (PubMed).

Alternatives for antigen "APG8b (MAP1LC3B)", type "Antibodies"
Hosts (4)
Reactivities (4), (1)
Applications (2), (2), (1), (1), (1)
Epitopes (1), (1), (1), (1), (1), (1), (1), (1)
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