Atlastin GTPase 3 (ATL3) (Center) antibody

Antigen: Atlastin GTPase 3 (ATL3)

Synonyms: DKFZp564J0863, AI465397, AW228836, MGC28761, 4633402C03Rik, 5730596K20Rik, RGD1309871, ATL3, MGC152382

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Hamster

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN650914

Additional Information

Alternative name: ATL3

Gene ID: 25923

UniProt: Q6DD88

Immunogen: This ATL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 230-260 from the Central region of human ATL3.

Isotype: Ig

Description: Other names: Atlastin-3,ATL3

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ATL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 230-260 from the Central region of human ATL3.

Molecular Weight: 60542 DA

Comments:

Background: ATL3 is GTPase tethering membranes through formation of trans-homooligomer and mediating homotypic fusion of endoplasmic reticulum membranes. ATL3 is function in endoplasmic reticulum tubular network biogenesis.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Signaling, Phospho-specific antibodies, Cell Structure, Protein Modifications, Chromatin, Metabolism

Restrictions: For Research Use only

Images

Western blot analysis of ATL3 Antibody (Center) (ABIN650914) in mouse liver tissue lysates (35ug/lane). ATL3 (arrow) was detected using the purified Pab.

Western blot analysis of ATL3 Antibody (Center) (ABIN650914) in CHO cell line lysates (35ug/lane). ATL3 (arrow) was detected using the purified Pab.

Publications

Product: Rismanchi, Soderblom, Stadler et al.: "Atlastin GTPases are required for Golgi apparatus and ER morphogenesis." in: Human molecular genetics, Vol. 17, Issue 11, pp. 1591-604, 2008 (PubMed).

Hu, Shibata, Zhu et al.: "A class of dynamin-like GTPases involved in the generation of the tubular ER network." in: Cell, Vol. 138, Issue 3, pp. 549-61, 2009 (PubMed).