Vacuolar Protein Sorting 52 (Yeast) (VPS52) (N-Term) antibody

Antigen: Vacuolar Protein Sorting 52 (Yeast) (VPS52)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN650930

Additional Information

Alternative name: SAC2

Gene ID: 22876

UniProt: Q9Y2H2

Immunogen: This SAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the N-terminal region of human SAC2.

Isotype: Ig

Description: Other names: Inositol polyphosphate 5-phosphatase F, Sac domain-containing phosphoinositide 5-phosphatase 2, hSAC2, Sac domain-containing inositol phosphatase 2, Phosphatidylinositide phosphatase SAC2,MSTP047, MSTP007, SAC2, KIAA0966, INPP5F

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This SAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140~169 amino acids from the N-terminal region of human SAC2.

Molecular Weight: 128407 DA

Comments:

Background: SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Protein Modifications, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

Western blot analysis of SAC2 Antibody (N-term) (ABIN650930) in WiDr cell line lysates (35ug/lane). SAC2 (arrow) was detected using the purified Pab.

Publications

Product: Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).