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Details for Product No. ABIN652195

Kallikrein 6 (KLK6) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms Bssp, Klk7, PRSS18, PRSS9, SP59, hK6, Prss9, AI849898, BSP, Klk29, MSP, Prss18, neurosin, klk6
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 3 references available
Catalog no. ABIN652195
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This Kallikrein 6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human Kallikrein 6.
Clone RB6114
Isotype Ig
Specificity This Kallikrein 6 Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human KLK6.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Background Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
Synonyms: Protease M, Neurosin, Zyme, SP59,
Molecular Weight 26856 DA
Gene ID 5653
UniProt Q92876
Research Area Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Sauter, Lininger, Magklara et al.: "Association of kallikrein expression in nipple aspirate fluid with breast cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 108, Issue 4, pp. 588-91, 2003 (PubMed).

Pampalakis, Kurlender, Diamandis et al.: "Cloning and characterization of novel isoforms of the human kallikrein 6 gene." in: Biochemical and biophysical research communications, Vol. 320, Issue 1, pp. 54-61, 2004 (PubMed).

Ghosh, Grass, Soosaipillai et al.: "Human kallikrein 6 degrades extracellular matrix proteins and may enhance the metastatic potential of tumour cells." in: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, Vol. 25, Issue 4, pp. 193-9, 2004 (PubMed).

Alternatives for antigen "Kallikrein 6 (KLK6)", type "Antibodies"
Hosts (27), (7), (4)
Reactivities (34), (15), (13), (1), (1)
Applications (25), (15), (10), (5), (4), (3), (3), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (2), (1), (1), (1)
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