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Kallikrein 6 Products

(Kallikrein 6 (KLK6))
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

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Featured Kallikrein 6 Categories

Kallikrein 6 Antibodies

High quality antibodies with extensive validation data.

Kallikrein 6 ELISA Kits

Reliable ELISA kits for a wide range of species.

Kallikrein 6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Kallikrein 6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
  • (6)
Cat. No. ABIN7432397
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7157217
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (4)
Cat. No. ABIN652195
Quantity 400 μL
Datasheet Datasheet

Recommended Kallikrein 6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
  • (1)
Cat. No. ABIN6957252
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957253
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957254
Quantity 96 tests
Datasheet Datasheet

Recommended Kallikrein 6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1308867
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7321290
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308865
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Kallikrein 6 products

Sells, Pandey, Chen, Skovan, Cui, Ignatenko: "Specific microRNA-mRNA Regulatory Network of Colon Cancer Invasion Mediated by Tissue Kallikrein-Related Peptidase 6." in: Neoplasia (New York, N.Y.), Vol. 19, Issue 5, pp. 396-411, (2018) (PubMed).

Ehrenfeld, Manso, Pavicic, Matus, Borquez, Lizama, Sarmiento, Poblete, Bhoola, Naran, Figueroa: "Bioregulation of kallikrein-related peptidases 6, 10 and 11 by the kinin B₁ receptor in breast cancer cells." in: Anticancer research, Vol. 34, Issue 12, pp. 6925-38, (2015) (PubMed).

Lou, Si, Chen, Sun, Zhang, Niu, Hu: "Correlation between KLK6 expression and the clinicopathological features of glioma." in: Contemporary oncology (Pozna?, Poland), Vol. 18, Issue 4, pp. 246-51, (2014) (PubMed).

Ashby, Kehoe, Love: "Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia." in: Brain research, Vol. 1363, pp. 1-10, (2010) (PubMed).

Pampalakis, Kurlender, Diamandis, Sotiropoulou: "Cloning and characterization of novel isoforms of the human kallikrein 6 gene." in: Biochemical and biophysical research communications, Vol. 320, Issue 1, pp. 54-61, (2004) (PubMed).

Bayés, Tsetsenis, Ventura, Vendrell, Aviles, Sotiropoulou: "Human kallikrein 6 activity is regulated via an autoproteolytic mechanism of activation/inactivation." in: Biological chemistry, Vol. 385, Issue 6, pp. 517-24, (2004) (PubMed).

Christophi, Isackson, Blaber, Blaber, Rodriguez, Scarisbrick: "Distinct promoters regulate tissue-specific and differential expression of kallikrein 6 in CNS demyelinating disease." in: Journal of neurochemistry, Vol. 91, Issue 6, pp. 1439-49, (2004) (PubMed).

Iwata, Maruyama, Akagi, Hashikawa, Kanazawa, Tsuji, Nukina: "Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2625-35, (2003) (PubMed).

Johnson, Drugan, Miller, Evans: "38" in: , Vol. 1363, Issue Nucleic acids research, pp. 28-39, (1991)

Synonyms and alternative names related to Kallikrein 6

kallikrein related peptidase 6 (KLK6), kallikrein related-peptidase 6 (Klk6), kallikrein-6 (LOC100716801), AI849898, BSP, Bssp, hK6, Klk7, Klk29, MSP, neurosin, PRSS9, Prss9, PRSS18, Prss18, SP59

Protein level used designations for Kallikrein 6

  • kallikrein-6
  • neurosin
  • protease M
  • serine protease 18
  • serine protease 9
  • zyme
  • kallikrein 6 (neurosin)
  • kallikrein 6 (neurosin, zyme)
  • protease serine 9 (neurosin)
  • protease, serine, 9
  • brain serine protease
  • kallikrein 29
  • kallikrein 6
  • myelencephalon-specific protease
  • myofibril-bound protease
  • protease, serine, 18
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