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NEK3 (Center) antibody
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Description||Other names: Serine/threonine-protein kinase Nek3, NimA-related protein kinase 3, HSPK 36|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This NEK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 339~368 amino acids from the center region of human NEK3.|
Background: In Aspergillus nidulans, lack of the serine/threonine kinase NimA (never in mitosis A) results in cell cycle arrest in G2, while overexpression causes the premature onset of mitotic events. NEK3 is similar in sequence to the Aspergillus nidulans protein and may therefore play a role in mitotic regulation. However, the encoded protein differs from other NimA family members in that it is not cell cycle regulated and is found primarily in the cytoplasm.
|Research Area||Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure|
|Restrictions||For Research Use only|
Schultz, Fry, Sütterlin et al.: "Cell cycle-dependent expression of Nek2, a novel human protein kinase related to the NIMA mitotic regulator of Aspergillus nidulans." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 5, Issue 6, pp. 625-35, 1994 (PubMed).
Schultz, Nigg: "Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 4, Issue 10, pp. 821-30, 1994 (PubMed).
Kimura, Okano: "Molecular cloning and characterization of the human NIMA-related protein kinase 3 gene (NEK3)." in: Cytogenetics and cell genetics, Vol. 95, Issue 3-4, pp. 177-82, 2002 (PubMed).
|Hosts||Rabbit (22), Mouse (1)|
|Reactivities||Human (21), Mouse (Murine) (20), Cow (Bovine) (19), Rat (Rattus) (19), Horse (Equine) (18), Pig (Porcine) (18), Chicken (1), Xenopus laevis (1)|
|Applications||Immunofluorescence (IF) (16), Western Blotting (WB) (8), ELISA (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)|
|Conjugates||Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)|
|Epitopes||C-Term (1), N-Term (1)|