|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Diaphanous Homolog 2 (Drosophila) (DIAPH2) (Center) antibody
|Synonyms||DIAPH2, Diap2, RGD1564399, DIAPH1, MGC148327, DIA, POF, DIA2, DRF2, POF2, mDia3, FLJ11167, DIA3, E430022I22Rik, dia2, sb:eu1025|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This DIAPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 877~907 amino acids from the Central region of human DIAPH2.|
|Description||Other names: Diaphanous-related formin-2, DRF2, Protein diaphanous homolog 2, DIA, DIAPH2|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This DIAPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 877~907 amino acids from the Central region of human DIAPH2.|
|Molecular Weight||125569 DA|
Background: DIAPH2 belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this protein have been linked to premature ovarian failure 2.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100 Flow cytometric~~1:10~50|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Signaling, Protein Modifications, Cancer, Cell Structure|
|Restrictions||For Research Use only|
Satoh, Tominaga: "mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation." in: The Journal of biological chemistry, Vol. 276, Issue 42, pp. 39290-4, 2001 (PubMed).
Gasman, Kalaidzidis, Zerial: "RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase." in: Nature cell biology, Vol. 5, Issue 3, pp. 195-204, 2003 (PubMed).
Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).
|Reactivities||Human (8), Mouse (Murine) (2), Rat (Rattus) (2)|
|Applications||Western Blotting (WB) (8), ELISA (4), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (2), Flow Cytometry (FACS) (1), Immunoprecipitation (IP) (1)|
|Epitopes||AA 1085-1101 (2), C-Term (2), AA 56-114 (1)|