|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Chromosome 11 Open Reading Frame 30 (C11orf30) (N-Term) antibody
|Synonyms||EMSY, GL002, FLJ90741, 2210018M11RIK|
Alternatives Western Blotting (WB), ELISA
|4 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53~83 amino acids from the N-terminal region of human C11orf30.|
|Description||Other names: Protein EMSY, GL002, C11orf30, EMSY|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53~83 amino acids from the N-terminal region of human C11orf30.|
|Molecular Weight||141468 DA|
Background: Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cancer, Transcription Factors, Signaling, Cell Structure|
|Restrictions||For Research Use only|
|Western blot analysis of C11orf30 Antibody (N-term) (ABIN653429) in Ramos cell line lysates (35ug/lane). C11orf30 (arrow) was detected using the purified Pab.|
Vega, Salas, Milne et al.: "Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study." in: Gynecologic oncology, Vol. 112, Issue 1, pp. 210-4, 2008 (PubMed).
Mavaddat, Dunning, Ponder et al.: "Common genetic variation in candidate genes and susceptibility to subtypes of breast cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 1, pp. 255-9, 2009 (PubMed).
Garapaty, Xu, Trojer et al.: "Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation." in: The Journal of biological chemistry, Vol. 284, Issue 12, pp. 7542-52, 2009 (PubMed).
Esparza-Gordillo, Weidinger, Fölster-Holst et al.: "A common variant on chromosome 11q13 is associated with atopic dermatitis." in: Nature genetics, Vol. 41, Issue 5, pp. 596-601, 2009 (PubMed).