Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1) (N-Term) antibody

Antigen: Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1)

Synonyms: MIPP, HIPER1, MINPP2, DKFZp564L2016, AA408516, minpp1, MGC56080, zgc:56080, zgc:76991, MGC134477, DKFZp469H164

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN654085

Additional Information

Alternative name: MINPP1

Gene ID: 9562

UniProt: NP_001171588.1, Q9UNW1, NP_001171589.1, NP_004888.2

Immunogen: This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human MINPP1.

Isotype: Ig

Description: Other names: Multiple inositol polyphosphate phosphatase 1,MINPP1,MIPP

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This MINPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-63 amino acids from the N-terminal region of human MINPP1.

Molecular Weight: 55051 DA

Comments:

Background: This gene encodes multiple inositol polyphosphate phosphatase, an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate, an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Protein Modifications, Metabolism, Cell Structure

Restrictions: For Research Use only

Images

MINPP1 Antibody (N-term) (ABIN654085) western blot analysis in murine erythroleukemia cell line lysates (35ug/lane). This demonstrates the MINPP1 antibody detected the MINPP1 protein (arrow).(Kindly offered by Doc. Norma)

Publications

Product: Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).