|+1 404 474 4654|
|+1 888 205 9894 (TF)|
ATP Synthase, H+ Transporting, Mitochondrial Fo Complex, Subunit D (ATP5H) (Center) antibody
|Synonyms||ATPQ, MGC128531, MGC82361|
Alternatives Western Blotting (WB), ELISA
|4 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|UniProt||NP_001003785.1, NP_006347.1, O75947|
|Immunogen||This ATP5H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the Central region of human ATP5H.|
|Description||Other names: ATP synthase subunit d, mitochondrial,ATP5H,|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This ATP5H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-105 amino acids from the Central region of human ATP5H.|
|Molecular Weight||18491 DA|
Background: Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 Immunohistochemistry ~~ 1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Signaling, Cell Signaling, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
Oster, Wang: "Rotary protein motors." in: Trends in cell biology, Vol. 13, Issue 3, pp. 114-21, 2003 (PubMed).
Cross: "Molecular motors: turning the ATP motor." in: Nature, Vol. 427, Issue 6973, pp. 407-8, 2004 (PubMed).
Kim, Kim, Yoo et al.: "Identification of mitochondrial F(1)F(0)-ATP synthase interacting with galectin-3 in colon cancer cells." in: Cancer science, Vol. 99, Issue 10, pp. 1884-91, 2008 (PubMed).
Martins-de-Souza, Gattaz, Schmitt et al.: "Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia." in: Journal of psychiatric research, Vol. 43, Issue 11, pp. 978-86, 2009 (PubMed).
|Reactivities||Human (12), Mouse (Murine) (8), Rat (Rattus) (5), Cat (Feline) (1), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (12), ELISA (10), Immunohistochemistry (IHC) (5), Immunofluorescence (IF) (3), Flow Cytometry (FACS) (1), Immunoprecipitation (IP) (1)|
|Epitopes||C-Term (5), Internal Region,AA 75-105 (1)|