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S6A12 (N-Term) antibody

Antigen

S6A12
Binding Site

N-Term
Clonality Polyclonal
Host

Rabbit
Reactivity

Human
Application
Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN654460
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information
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Gene ID 6539
UniProt P48065, NP_003035.3, NP_001116320.1, NP_001116319.1
Immunogen This S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human S6A12.
Isotype Ig
Description Other names: SLC6A12,Sodium- and chloride-dependent betaine transporter,
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human S6A12.
Molecular Weight 69368 DA
Comments

Background: Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cell Structure, Protein Modifications, Neurology
Restrictions For Research Use only

Publications
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Product Köttgen, Pattaro, Böger et al.: "New loci associated with kidney function and chronic kidney disease." in: Nature genetics, Vol. 42, Issue 5, pp. 376-84, 2010 (PubMed).

Pasaje, Kim, Park et al.: "Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population." in: Annals of human genetics, Vol. 74, Issue 4, pp. 326-34, 2010 (PubMed).