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Complement Component 5a Receptor 1 (C5AR1) (Center) antibody

Antigen

Complement Component 5a Receptor 1 (C5AR1)

Synonyms C5A, C5AR, C5R1, CD88, C5aR, C5r1, Cd88, D7Msu1, C5AR1, GPR77, C5ar1
Binding Site
Alternatives

Center

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN654658
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name C5AR1
Gene ID 728
UniProt NP_001727.1, P21730
Immunogen This C5AR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human C5AR1.
Isotype Ig
Description Other names: C5a anaphylatoxin chemotactic receptor,C5AR1,C5AR, C5R1
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This C5AR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-205 amino acids from the Central region of human C5AR1.
Molecular Weight 39336 DA
Comments

Background: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Restrictions For Research Use only

Publications

Product Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Marc, Kristan, Rozman et al.: "Complement factor C5a in acute exacerbation of Chronic Obstructive Pulmonary Disease." in: Scandinavian journal of immunology, Vol. 71, Issue 5, pp. 386-91, 2010 (PubMed).