|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Intercellular Adhesion Molecule 2 (ICAM2) (Center) antibody
|Synonyms||CD102, ICAM-2, MGC95023, ICAM2, Ly-60, Icam-2|
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|UniProt||NP_000864.2, NP_001093256.1, P13598, NP_001093259.1, NP_001093258.1, NP_001093257.1|
|Immunogen||This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.|
|Description||Other names: Intercellular adhesion molecule 2,ICAM2,|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.|
|Molecular Weight||30654 DA|
Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Cell Signaling, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
|ICAM2 Antibody (Center) (ABIN655000) western blot analysis in HepG2 cell line lysates (35ug/lane). This demonstrates the ICAM2 antibody detected the ICAM2 protein (arrow).|
Sato, Azuma, Higai et al.: "Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins." in: Biochimica et biophysica acta, Vol. 1790, Issue 10, pp. 1198-205, 2009 (PubMed).
Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).
Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).