Intercellular Adhesion Molecule 2 (ICAM2) (Center) antibody
| Antigen | Intercellular Adhesion Molecule 2 (ICAM2) |
| Synonyms | CD102, ICAM-2, MGC95023, ICAM2, Ly-60, Icam-2 |
| Binding Site |
 Alternatives Center |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Western Blotting (WB), ELISA |
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3 references available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN655000 |
| Quantity | 0.1 mg (0.25 mg/ml) |
| Price | 280.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Alternative name | ICAM2 |
| Gene ID | 3384 |
| UniProt | NP_000864.2, NP_001093256.1, P13598, NP_001093259.1, NP_001093258.1, NP_001093257.1 |
| Immunogen | This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2. |
| Isotype | Ig |
| Description | Other names: Intercellular adhesion molecule 2,ICAM2, |
| Characteristics | Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Specificity | This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2. |
| Molecular Weight | 30654 DA |
| Comments |
Background: The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. |
Application Details
| Application Notes | The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 |
| Concentration | 0.25 mg/ml |
| Purification | Purified |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles |
| Research Area | Cell Signaling, Protein Modifications, Cell Structure |
| Restrictions | For Research Use only |
Images
| ICAM2 Antibody (Center) (ABIN655000) western blot analysis in HepG2 cell line lysates (35ug/lane). This demonstrates the ICAM2 antibody detected the ICAM2 protein (arrow). |
Publications
| Product |
Sato, Azuma, Higai et al.: "Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins." in: Biochimica et biophysica acta, Vol. 1790, Issue 10, pp. 1198-205, 2009 (PubMed).
Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed). Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed). |
Alternatives
Alternatives for antigen "Intercellular Adhesion Molecule 2 (ICAM2)", type "Antibodies"
