TNFSF4 antibody (AA 97-125)

Catalog No. ABIN655028

The Rabbit Polyclonal anti-TNFSF4 antibody is suitable to detect TNFSF4 in samples from Human. It has been validated for WB and FACS.

Quick Overview for TNFSF4 antibody (AA 97-125) (ABIN655028)

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFSF4 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB30006

Product Details anti-TNFSF4 Antibody

Binding Specificity: AA 97-125

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNFSF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-125 amino acids from the Central region of human TNFSF4.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TNFSF4

Target: TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4 (TNFSF4))

Alternative Name: TNFSF4

Background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.

Molecular Weight: 21050

Gene ID: 7292

NCBI Accession: NP_003317

UniProt: P23510

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation, Cancer Immune Checkpoints