Asparaginyl-tRNA Synthetase (NARS) (N-Term) antibody

Antigen: Asparaginyl-tRNA Synthetase (NARS)

Synonyms: ASNRS, NARS1, AsnRS, BcDNA:GH06451, Ca, CG10687, DmelCG10687, l(2)37Ca, l(2)37Ca)E11, l(2)E11, NRS, C78150, AA960128, 3010001M15Rik, MGC116236, LRRGT00113, fb57a10, wu:fb57a10, si:dkey-274m14.2, NARS, MGC127700, MGC125113, RGD1305145

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655041

Additional Information

Alternative name: NARS

Gene ID: 4677

UniProt: NP_004530.1, O43776

Immunogen: This NARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human NARS.

Isotype: Ig

Description: Other names: Asparaginyl-tRNA synthetase, cytoplasmic,NARS,

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This NARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human NARS.

Molecular Weight: 62943 DA

Comments:

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases.

Synonyms: ASNRS, NARS1, AsnRS, BcDNA:GH06451, Ca, CG10687, DmelCG10687, l(2)37Ca, l(2)37Ca)E11, l(2)E11, NRS, C78150, AA960128, 3010001M15Rik, MGC116236, LRRGT00113, fb57a10, wu:fb57a10, si:dkey-274m14.2, NARS, MGC127700, MGC125113, RGD1305145

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry ~~ 1:50~100

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca

Research Area: Translation Factors, Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure

Restrictions: For Research Use only

Publications

Product: Cirullo, Arredondo-Vega, Smith et al.: "Isolation and characterization of interspecific heat-resistant hybrids between a temperature-sensitive chinese hamster cell asparaginyl-tRNA synthetase mutant and normal human leukocytes: assignment of human asnS gene to chromosome 18." in: Somatic cell genetics, Vol. 9, Issue 2, pp. 215-33, 1983 (PubMed).

Beaulande, Tarbouriech, Härtlein: "Human cytosolic asparaginyl-tRNA synthetase: cDNA sequence, functional expression in Escherichia coli and characterization as human autoantigen." in: Nucleic acids research, Vol. 26, Issue 2, pp. 521-4, 1998 (PubMed).

Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).