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Immediate Early Response 3 (IER3) (N-Term) antibody

Antigen

Immediate Early Response 3 (IER3)
Synonyms DIF2, IEX1, PRG1, DIF-2, GLY96, IEX-1, IEX-1L, cI-3, gly96, AI663993, IER3, MGC140531
Binding Site
Alternatives

N-Term
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN655735
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information
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Alternative name IER3
Gene ID 8870
UniProt P46695, NP_003888.2
Immunogen This IER3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human IER3.
Isotype Ig
Description Other names: IER3,Radiation-inducible immediate-early gene IEX-1,DIF2, IEX1, PRG1
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This IER3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human IER3.
Molecular Weight 16929 DA
Comments

Background: This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.

Application Details
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Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cell Signaling, Cell Structure, Protein Modifications
Restrictions For Research Use only

Publications
Application Details Alternatives back to top

Product Do, Ucisik-Akkaya, Davis et al.: "TP53 R72P and MDM2 SNP309 polymorphisms in modification of childhood acute lymphoblastic leukemia susceptibility." in: Cancer genetics and cytogenetics, Vol. 195, Issue 1, pp. 31-6, 2009 (PubMed).

Fellay, Ge, Shianna et al.: "Common genetic variation and the control of HIV-1 in humans." in: PLoS genetics, Vol. 5, Issue 12, pp. e1000791, 2009 (PubMed).

Alternatives
Application Details Publications back to top

Alternatives for antigen "Immediate Early Response 3 (IER3)", type "Antibodies"
Hosts Rabbit (25)
Reactivities Human (24), Mouse (Murine) (19)
Applications Immunofluorescence (IF) (14), Western Blotting (WB) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), ELISA (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunohistochemistry (IHC) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes Internal Region (1), Middle Region (1), N-Term (1)