Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2) (C-Term) antibody

Antigen: Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2)

Synonyms: MGC10562, MGC37615, FRAT2

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655793

Additional Information

Alternative name: FRAT2

Gene ID: 23401

UniProt: O75474, NP_036215.1

Immunogen: This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-233 amino acids from the C-terminal region of human FRAT2.

Isotype: Ig

Description: Other names: FRAT2,GSK-3-binding protein FRAT2,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-233 amino acids from the C-terminal region of human FRAT2.

Molecular Weight: 24051 DA

Comments:

Background: The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Cell Structure

Restrictions: For Research Use only

Publications

Product: Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).