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Growth Arrest-Specific 1 (GAS1) (N-Term) antibody

Antigen

Growth Arrest-Specific 1 (GAS1)

Synonyms Gas-1, AW554192, MGC147541
Binding Site
Alternatives

N-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN655812
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name GAS1
Gene ID 2619
UniProt P54826, NP_002039
Immunogen This GAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the N-terminal region of human GAS1.
Isotype Ig
Description Other names: Growth arrest-specific protein 1,GAS1,
Characteristics Purified Rabbit Polyclonal Antibody (Pab)
Specificity This GAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the N-terminal region of human GAS1.
Molecular Weight 35693 DA
Comments

Background: Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100 Immunohistochemistry ~~ 1:50~100
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle
Restrictions For Research Use only

Publications

Product Zhao, Pan, Gang et al.: "Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26273-85, 2009 (PubMed).

Rittié, Stoll, Kang et al.: "Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin." in: Aging cell, Vol. 8, Issue 6, pp. 738-51, 2009 (PubMed).

Alternatives

Alternatives for antigen "Growth Arrest-Specific 1 (GAS1)", type "Antibodies"
Hosts Rabbit (26)
Reactivities Human (26), Mouse (Murine) (22), Chicken (17), Cow (Bovine) (17), Dog (Canine) (17), Pig (Porcine) (17), Rat (Rattus) (17), Sheep (Ovine) (17)
Applications Immunofluorescence (IF) (15), Western Blotting (WB) (11), ELISA (8), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Dot Blot (DB) (1), Flow Cytometry (FACS) (1), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (4)