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Forkhead Box A2 (FOXA2) (C-Term) antibody
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human FOXA2.|
|Description||Other names: FOXA2,Hepatocyte nuclear factor 3-beta,HNF3B, TCF3B|
|Characteristics||Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human FOXA2.|
|Molecular Weight||48306 DA|
Background: This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
|Synonyms||HNF3B, TCF3B, MGC19807, Hnf3b, Tcf3b, Hnf-3b, Tcf-3b, HNF3beta, HNF3-beta, ax, axl, fkd1, HNF-3B, MGC101552, tdsubc_2g8, wu:fe05g04, ik:tdsubc_2g8, xx:tdsubc_2g8, hnf3b, tcf3b, hnf3beta, hnf3-beta, FOXA2, HNF-3BETA, HNF-3b, xFD-3, FoxA2a, FoxA2-A, xbeta-1|
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure|
|Restrictions||For Research Use only|
Xing, Cohen, Boerwinkle: "A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels." in: American journal of human genetics, Vol. 86, Issue 3, pp. 440-6, 2010 (PubMed).
Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).
Dayoub, Groitl, Dobner et al.: "Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 465-70, 2010 (PubMed).
|Hosts||Mouse (18), Rabbit (18), Goat (8)|
|Reactivities||Human (39), Mouse (Murine) (10), Rat (Rattus) (6), Dog (Canine) (3), Xenopus laevis (2), Chicken (1), Cow (Bovine) (1), Zebrafish (1)|
|Applications||Western Blotting (WB) (43), ELISA (27), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (12), Immunofluorescence (IF) (11), Immunohistochemistry (IHC) (7), Immunocytochemistry (ICC) (3), Immunoprecipitation (IP) (2), Flow Cytometry (FACS) (1)|
|Epitopes||C-Term (4), Center (2), Internal Region (2), AA 350-361 (1), Center, Thr156 (1), Met10 (1), Met12 (1), N-Term (1), Transcript Variant 2 (1)|