Zinc Finger, FYVE Domain Containing 1 (ZFYVE1) (N-Term) antibody

Antigen: Zinc Finger, FYVE Domain Containing 1 (ZFYVE1)

Synonyms: DFCP1, TAFF1, ZNFN2A1, KIAA1589, mKIAA1589, G630053K23, MGC84406, DKFZp469G0722

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656392

Additional Information

Alternative name: ZFYVE1

Gene ID: 53349

UniProt: NP_848535.1, Q9HBF4, NP_067083.1

Immunogen: This ZFYVE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human ZFYVE1.

Isotype: Ig

Description: Other names: ZFYVE1,Zinc finger FYVE domain-containing protein 1,DFCP1, KIAA1589, TAFF1, ZNFN2A1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This ZFYVE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-173 amino acids from the N-terminal region of human ZFYVE1.

Molecular Weight: 87176 DA

Comments:

Background: The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: ZFYVE1 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Cell Structure

Restrictions: For Research Use only

Images

ZFYVE1 Antibody (N-term) (ABIN656392) western blot analysis in human placenta tissue lysates (35ug/lane). This demonstrates the ZFYVE1 antibody detected the ZFYVE1 protein (arrow).

Publications

Product: Krugmann, Anderson, Ridley et al.: "Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices." in: Molecular cell, Vol. 9, Issue 1, pp. 95-108, 2002 (PubMed).

Heilig, Eckenberg, Petit et al.: "The DNA sequence and analysis of human chromosome 14." in: Nature, Vol. 421, Issue 6923, pp. 601-7, 2003 (PubMed).

Wan, Gong, Qin et al.: "Large-scale cDNA transfection screening for genes related to cancer development and progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 44, pp. 15724-9, 2004 (PubMed).