F-Box Protein 41 (FBXO41) (N-Term) antibody

Antigen: F-Box Protein 41 (FBXO41)

Synonyms: FBX41, FLJ37709, 9630017H13, D6Ertd538e, fbx41, MGC146326

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656516

Additional Information

Alternative name: FBX41

Gene ID: 150726

UniProt: Q8TF61, NP_001073879.2

Immunogen: This FBX41 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the N-terminal region of human FBX41.

Isotype: Ig

Description: Other names: F-box only protein 41,FBXO41,FBX41, KIAA1940

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This FBX41 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-263 amino acids from the N-terminal region of human FBX41.

Molecular Weight: 94510 DA

Comments:

Background: Members of the F-box protein family, such as FBXO41, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: FBX41 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Signaling, Phospho-specific antibodies, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

FBX41 Antibody (N-term) (ABIN656516) western blot analysis in mouse cerebellum tissue lysates (35ug/lane). This demonstrates the FBX41 antibody detected the FBX41 protein (arrow).

Publications

Product: Watanabe, Arai, Nishihara et al.: "M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFbeta-TrCP." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 13, pp. 4419-24, 2004 (PubMed).

Jin, Cardozo, Lovering et al.: "Systematic analysis and nomenclature of mammalian F-box proteins." in: Genes & development, Vol. 18, Issue 21, pp. 2573-80, 2004 (PubMed).