Keratocan (KERA) (C-Term) antibody

Antigen: Keratocan (KERA)

Synonyms: CNA2, SLRR2B, KERA, MGC143305, MGC136259, zgc:136259, si:dkeyp-38g8.3

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656548

Additional Information

Alternative name: KERA

Gene ID: 11081

UniProt: O60938, NP_008966.1

Immunogen: This KERA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-257 amino acids from the C-terminal region of human KERA.

Isotype: Ig

Description: Other names: Keratocan,KERA,SLRR2B

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This KERA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-257 amino acids from the C-terminal region of human KERA.

Molecular Weight: 40509 DA

Comments:

Background: The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: KERA Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

KERA Antibody (C-term) (ABIN656548) western blot analysis in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the KERA antibody detected the KERA protein (arrow).

Publications

Product: Wheeler, Metter, Tanaka et al.: "Sequential use of transcriptional profiling, expression quantitative trait mapping, and gene association implicates MMP20 in human kidney aging." in: PLoS genetics, Vol. 5, Issue 10, pp. e1000685, 2009 (PubMed).