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Antibodies
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anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) (Center) antibody
gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) (Center) antibody
| Antigen |
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| Synonyms |
GABRA4 |
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Binding Site
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Human (41), Rat (Rattus) (36), Mouse (Murine) (28), Chicken (19), Horse (Equine) (18), Pig (Porcine) (18), Rabbit (18), Sheep (Ovine) (18), Cow (Bovine) (5), Cat (Feline) (1), Dog (Canine) (1)
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Conjugate
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Application
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| Catalog no. |
ABIN656594 |
| Quantity |
0.1 mg (0.25 mg/ml) (Variants) |
| Price |
280.50 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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GABRA4
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Gene ID
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2557
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UniProt
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P48169, NP_000800.2
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Immunogen
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This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human GABRA4.
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Isotype
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Ig
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Description
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Other names: Gamma-aminobutyric acid receptor subunit alpha-4,GABRA4,
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Characteristics
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Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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Specificity
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This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human GABRA4.
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Molecular Weight
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61623 DA
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Comments
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Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
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Application Notes
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The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
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Concentration
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0.25 mg/ml
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Purification
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Purified
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Buffer
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage
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GABRA4 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.
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Research Area
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Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Neurology
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Restrictions
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For Research Use only
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Product
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Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).
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Alternatives for antigen "gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4)", type "Antibodies"
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Hosts
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Rabbit (46), Goat (6)
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Reactivities
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Human (41), Rat (Rattus) (36), Mouse (Murine) (28), Chicken (19), Horse (Equine) (18), Pig (Porcine) (18), Rabbit (18), Sheep (Ovine) (18), Cow (Bovine) (5), Cat (Feline) (1), Dog (Canine) (1)
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Applications
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Western Blotting (WB) (36), ELISA (21), Immunofluorescence (IF) (16), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (IHC) (4), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Flow Cytometry (FACS) (2), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
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Conjugates
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Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
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Epitopes
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Internal Region (7), N-Term (5), C-Term (4), Center (1), Cytoplasmic Domain (1), Internal Region,AA 340-369 (1), Internal Region,AA 356-386 (1), Subunit alpha 4 (1)
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Alternatives 
