Interferon, alpha-Inducible Protein 6 (IFI6) (N-Term) antibody

Antigen: Interferon, alpha-Inducible Protein 6 (IFI6)

Synonyms: 6-16, G1P3, FAM14C, IFI616, IFI-6-16, MGC137037

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656889

Additional Information

Alternative name: IFI6

Gene ID: 2537

UniProt: P09912, NP_002029.3, NP_075011.1

Immunogen: This IFI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human IFI6.

Isotype: Ig

Description: Other names: Interferon alpha-inducible protein 6,IFI6,G1P3

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This IFI6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-34 amino acids from the N-terminal region of human IFI6.

Molecular Weight: 12927 DA

Comments:

Background: This gene was first identified as one of the many genes induced by interferon. The encoded protein may play a critical role in the regulation of apoptosis. A minisatellite that consists of 26 repeats of a 12 nucleotide repeating element resembling the mammalian splice donor consensus sequence begins near the end of the second exon. Alternatively spliced transcript variants that encode different isoforms by using the two downstream repeat units as splice donor sites have been described.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: IFI6 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Cell Signaling, Cell Structure

Restrictions: For Research Use only

Images

IFI6 Antibody (N-term) (ABIN656889) western blot analysis in MDA-MB453,CEM cell line lysates (35ug/lane). This demonstrates the IFI6 antibody detected the IFI6 protein (arrow).

Publications

Product: Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).