RAS, Dexamethasone-Induced 1 (RASD1) (C-Term) antibody

Antigen: RAS, Dexamethasone-Induced 1 (RASD1)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657026

Additional Information

Alternative name: RASD1

Isotype: Ig

Description: Other names: Dexamethasone-induced Ras-related protein 1,RASD1,AGS1, DEXRAS1

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-278 amino acids from the C-terminal region of human RASD1.

Comments:

Background: This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.

Application Details

Concentration: 0.25 mg/ml

Purification: Purified

Research Area: Signaling, Protein Modifications, Cell Structure, Chromatin

Restrictions: For Research Use only

Publications

Product: Lau, Chan, Perkinton et al.: "Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34728-37, 2008 (PubMed).

Nojima, Maruyama, Yasui et al.: "Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4356-64, 2009 (PubMed).