Delta(4)-Desaturase, Sphingolipid 1 (DEGS1) (N-Term) antibody

Antigen: Delta(4)-Desaturase, Sphingolipid 1 (DEGS1)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657334

Additional Information

Alternative name: DEGS1

Isotype: Ig

Description: Other names: Sphingolipid delta(4)-desaturase DES1,DEGS1,DES1, MLD

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This DEGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DEGS1.

Comments:

Background: This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.

Application Details

Concentration: 0.25 mg/ml

Purification: Purified

Research Area: Phospho-specific antibodies, Cell Structure, Protein Modifications, Metabolism

Restrictions: For Research Use only

Images

DEGS1 Antibody (N-term) (ABIN657334) western blot analysis in T47D cell line lysates (35ug/lane). This demonstrates the DEGS1 antibody detected the DEGS1 protein (arrow).

Publications

Product: Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).