Complement Component C9 (C9) (Center) antibody

Antigen: Complement Component C9 (C9)

Synonyms: C9, LOC100037951, LOC100136130

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657704

Additional Information

Alternative name: C9

Gene ID: 735

UniProt: P02748, NP_001728.1

Immunogen: This C9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-220 amino acids from the Central region of human C9.

Isotype: Ig

Description: Other names: Complement component C9,C9,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This C9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 190-220 amino acids from the Central region of human C9.

Molecular Weight: 63173 DA

Comments:

Background: This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: C9 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

C9 Antibody (Center) (ABIN657704) western blot analysis in ZR-75-1 cell line lysates (35ug/lane). This demonstrates the C9 antibody detected the C9 protein (arrow).

Publications

Product: Hofsteenge, Blommers, Hess et al.: "The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues." in: The Journal of biological chemistry, Vol. 274, Issue 46, pp. 32786-94, 2000 (PubMed).

Bunkenborg, Pilch, Podtelejnikov et al.: "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry." in: Proteomics, Vol. 4, Issue 2, pp. 454-65, 2004 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).