Lysosomal Protein Transmembrane 4 alpha (LAPTM4A) (N-Term) antibody

Antigen: Lysosomal Protein Transmembrane 4 alpha (LAPTM4A)

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657737

Additional Information

Alternative name: LAPTM4A

Gene ID: 9741

UniProt: Q15012, NP_055528.1

Immunogen: This LAPTM4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LAPTM4A.

Isotype: Ig

Description: Other names: Lysosomal-associated transmembrane protein 4A,LAPTM4A,KIAA0108, LAPTM4, MBNT, MTRP

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This LAPTM4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human LAPTM4A.

Molecular Weight: 26801 DA

Comments:

Background: This gene encodes a protein that has four predicted transmembrane domains. The function of this gene has not yet been determined, however, studies in the mouse homolog suggest a role in the transport of small molecules across endosomal and lysosomal membranes.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: LAPTM4A Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

LAPTM4A Antibody (N-term) (ABIN657737) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the LAPTM4A antibody detected the LAPTM4A protein (arrow).

Publications

Product: Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).