RAB6B, Member RAS Oncogene Family (RAB6B) (C-Term) antibody

Antigen: RAB6B, Member RAS Oncogene Family (RAB6B)

Synonyms: Rab6, Rab6b, RCO4-3, wu:fj49d11

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657771

Additional Information

Alternative name: RAB6B

Gene ID: 51560

UniProt: Q9NRW1, NP_057661.3

Immunogen: This RAB6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-195 amino acids from the C-terminal region of human RAB6B.

Isotype: Ig

Description: Other names: Ras-related protein Rab-6B,RAB6B,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This RAB6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-195 amino acids from the C-terminal region of human RAB6B.

Molecular Weight: 23462 DA

Comments:

Background: RAB6B seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: RAB6B Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Signaling, Cell Structure, Protein Modifications, Chromatin

Restrictions: For Research Use only

Images

RAB6B Antibody (C-term) (ABIN657771) western blot analysis in CEM cell line lysates (35ug/lane). This demonstrates the RAB6B antibody detected the RAB6B protein (arrow).

Publications

Product: Wu, Ma, Brown et al.: "Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening." in: Proteomics, Vol. 7, Issue 11, pp. 1775-85, 2007 (PubMed).

Wanschers, van de Vorstenbosch, Schlager et al.: "A role for the Rab6B Bicaudal-D1 interaction in retrograde transport in neuronal cells." in: Experimental cell research, Vol. 313, Issue 16, pp. 3408-20, 2007 (PubMed).

Wanschers, van de Vorstenbosch, Wijers et al.: "Rab6 family proteins interact with the dynein light chain protein DYNLRB1." in: Cell motility and the cytoskeleton, Vol. 65, Issue 3, pp. 183-96, 2008 (PubMed).