Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (Center) antibody

Antigen: Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4)

Synonyms: h731, MGC69337, PDCD4

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657922

Additional Information

Alternative name: PDCD4

Gene ID: 27250

UniProt: NP_055271.2, Q53EL6, NP_663314.1

Immunogen: This PDCD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the Central region of human PDCD4.

Isotype: Ig

Description: Other names: Programmed cell death protein 4,27250,H731

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This PDCD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the Central region of human PDCD4.

Molecular Weight: 51721 DA

Comments:

Background: This gene encodes a protein localized to the nucleus in proliferating cells. Expression of this gene is modulated by cytokines in natural killer and T cells. The gene product is thought to play a role in apoptosis but the specific role has not yet been determined. Two transcripts encoding different isoforms have been identified.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: PDCD4 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Ubiquitin-related antibodies, Apoptosis/Necrosis, Phospho-specific antibodies, Protein Modifications, Cancer, Chromatin, Signaling, Cell Structure

Restrictions: For Research Use only

Images

PDCD4 Antibody (Center) (ABIN657922) western blot analysis in HL-60 cell line lysates (35ug/lane). This demonstrates the PDCD4 antibody detected the PDCD4 protein (arrow).

Publications

Product: Hayashi, Aishima, Miyasaka et al.: "Pdcd4 expression in intraductal papillary mucinous neoplasm of the pancreas: its association with tumor progression and proliferation." in: Human pathology, Vol. 41, Issue 11, pp. 1507-15, 2010 (PubMed).