TNINI3 (AA 52-79) antibody
Quick Overview for TNINI3 (AA 52-79) antibody (ABIN658916)
Target
Reactivity
Host
Clonality
Application
Clone
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Binding Specificity
- AA 52-79
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Predicted Reactivity
- B, Hs, Rb
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Purification
- Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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Immunogen
- This TNINI3 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from human TNINI3.
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Isotype
- IgM
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Application Notes
- WB: 1:500~8000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- TNINI3
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Background
- Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
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Molecular Weight
- 24008
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NCBI Accession
- NP_000354
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UniProt
- P19429
Target
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