ITGA6 antibody

Catalog No. ABIN658988

The Mouse Monoclonal anti-ITGA6 antibody has been validated for FACS, IF and IHC (p). It is suitable to detect ITGA6 in samples from Human. There is 1 publication available.

Quick Overview for ITGA6 antibody (ABIN658988)

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 129CT49-6-5

Product Details anti-ITGA6 Antibody

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: ITA6 recombinant protein is used to produce this monoclonal antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: IF: 1:10~50. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ITGA6 antibody (ABIN658988)

Hu, Fang, Wang, Luk, Thamphiwatana, Dehaini, Nguyen, Angsantikul, Wen, Kroll, Carpenter, Ramesh, Qu, Patel, Zhu, Shi, Hofman, Chen, Gao, Zhang, Chien, Zhang: "Nanoparticle biointerfacing by platelet membrane cloaking." in: Nature, Vol. 526, Issue 7571, pp. 118-21, (2015) (PubMed).

Target Details for ITGA6

Target: ITGA6 (Integrin, alpha 6 (ITGA6))

Alternative Name: ITA6

Background: The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 126606

Gene ID: 3655

NCBI Accession: NP_000201, NP_001073286

UniProt: P23229

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex