DPF2 antibody

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Antigen
Synonyms im:7146797, zgc:101789, Requiem, req, req-A, ubi-d4, xReq, REQ, UBID4, 2210010M07Rik, Req
Reactivity
Hamster, Human
(78), (43), (24), (5), (5), (4), (4), (3), (1)
Host
Mouse
(60), (20)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(67), (37), (20), (13), (12), (11), (3), (2), (2), (1)
Pubmed 4 references available
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Quantity 0.1 mL
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Immunogen This DPF2 monoclonal antibody is generated from mouse immunized with DPF2 recombinant protein.
Clone 226CT14-1-1-2
Isotype IgG3, kappa
Specificity This DPF2 monoclonal antibody is generated from mouse immunized with DPF2 recombinant protein.
Purification Ascites
Background The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
Synonyms: 226CT14.1.1.2
Molecular Weight 44155 DA
Gene ID 5977
NCBI Accession NP_006259
UniProt Q92785
Research Area Apoptosis/Necrosis, Cell Structure, Signaling, Protein Modifications, Phospho-specific antibodies, Transcription Factors
Application Notes WB = 1:1000-32000
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DPF2 antibody (ABIN659113) DPF2 antibody western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This...
Western Blotting (WB) image for anti-DPF2 antibody (ABIN659113) DPF2 antibody western blot analysis in CHO cell line lysates (35ug/lane).This demon...
Background publications Tando, Ishizaka, Watanabe et al.: "Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 21951-60, 2010 (PubMed).

Matsuyama, Takada, Yokoyama et al.: "Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor alpha through histone deacetylase 1." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18166-76, 2010 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Catalog No. ABIN659113
$324.50
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