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Details for Product No. ABIN659113

DPF2 antibody

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Synonyms Req, ubi-d4, 2210010M07Rik, REQ, UBID4, im:7146797, zgc:101789, req, xReq, req-A, Requiem
»Alternatives Human, Hamster
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN659113
Quantity 0.1 mL
291.50 $   Plus shipping costs $45.00
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Immunogen This DPF2 monoclonal antibody is generated from mouse immunized with DPF2 recombinant protein.
Clone 226CT14-1-1-2
Isotype IgG3, kappa
Specificity This DPF2 monoclonal antibody is generated from mouse immunized with DPF2 recombinant protein.
Purification Ascites
Background The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
Synonyms: 226CT14.1.1.2
Molecular Weight 44155 DA
Gene ID 5977
UniProt Q92785, NP_006259.1
Research Area Apoptosis/Necrosis, Cell Structure, Signaling, Protein Modifications, Phospho-specific antibodies, Transcription Factors
Application Notes Recommend dilutions: WB : 1:1000-32000
Restrictions For Research Use only
Format Liquid
Buffer Crude ascites with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Matsuyama, Takada, Yokoyama et al.: "Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor alpha through histone deacetylase 1." in: The Journal of biological chemistry, Vol. 285, Issue 24, pp. 18166-76, 2010 (PubMed).

Tando, Ishizaka, Watanabe et al.: "Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway." in: The Journal of biological chemistry, Vol. 285, Issue 29, pp. 21951-60, 2010 (PubMed).

Alternatives for antigen "DPF2", type "Antibodies"
Hosts (44), (12)
Reactivities (56), (34), (17), (15), (15), (4), (4), (3), (1)
Applications (44), (29), (11), (9), (9), (3), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (8), (7), (4), (3), (2), (1), (1)