ADAMTS7 antibody (AA 241-340) (Biotin)

Catalog No. ABIN672488

The Rabbit Polyclonal anti-ADAMTS7 antibody is suitable to detect ADAMTS7 in samples from Rat and Mouse. It has been validated for WB, ELISA, IHC (fro) and IHC (p).

Quick Overview for ADAMTS7 antibody (AA 241-340) (Biotin) (ABIN672488)

Target: ADAMTS7 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS7 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADAMTS7 Antibody (Biotin)

Binding Specificity: AA 241-340

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse ADAMTS7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ADAMTS7

Target: ADAMTS7 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7))

Alternative Name: ADAMTS7

Background:

Synonyms: ADAM-TS7, ADAMTS7B, A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAM-TS 7, ADAMTS-7, COMPase, Adamts7

Background: Metalloprotease that may play a role in the degradation of COMP. Binds 1 zinc ion per subunit. pH dependence: Optimum pH is between 7.5 and 9.5. [Subcellular location] Secreted, extracellular space, extracellular matrix (By similarity). Note=Also found associated with the external cell surface[Tissue specificity] Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. Up-regulated in articular cartilage and synovium from arthritis patients.

Gene ID: 108153

UniProt: Q68SA9