ADAMTS7 antibody (AA 241-340) (HRP)

Catalog No. ABIN672495

The HRP-conjugated Rabbit Polyclonal anti-ADAMTS7 antibody (ABIN672495) specifically detects ADAMTS7 in WB, ELISA, IHC (fro) and IHC (p). The antibody is reactive with Rat and Mouse samples.

Quick Overview for ADAMTS7 antibody (AA 241-340) (HRP) (ABIN672495)

Target: ADAMTS7 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS7 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADAMTS7 Antibody (HRP)

Binding Specificity: AA 241-340

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse ADAMTS7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADAMTS7

Target: ADAMTS7 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 7 (ADAMTS7))

Alternative Name: ADAMTS7

Background:

Synonyms: ADAM-TS7, ADAMTS7B, A disintegrin and metalloproteinase with thrombospondin motifs 7, ADAM-TS 7, ADAMTS-7, COMPase, Adamts7

Background: Metalloprotease that may play a role in the degradation of COMP. Binds 1 zinc ion per subunit. pH dependence: Optimum pH is between 7.5 and 9.5. [Subcellular location] Secreted, extracellular space, extracellular matrix (By similarity). Note=Also found associated with the external cell surface[Tissue specificity] Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Detected in meniscus, bone, tendon, cartilage, synovium, fat and ligaments. Up-regulated in articular cartilage and synovium from arthritis patients.

Gene ID: 108153

UniProt: Q68SA9