CD161 antibody (AA 151-225)
Quick Overview for CD161 antibody (AA 151-225) (ABIN680998)
Target
See all CD161 (KLRB1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 151-225
-
Cross-Reactivity
- Human, Rat
-
Purification
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human CD161/NK11
-
Isotype
- IgG
-
-
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-188) antibody
KLRB1 Reactivity: Human WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 67-225) antibodyKLRB1 Reactivity: Human FACS, ELISA Host: Mouse Monoclonal 4C6A11 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Human, Non-Human Primate FACS, WB, IHC (fro) Host: Mouse Monoclonal HP-3G10 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (PE)KLRB1 Reactivity: Rat FACS Host: Mouse Monoclonal 10-78 PE
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Rat FACS, WB, IP, IHC (fro), RIA Host: Mouse Monoclonal 10-78 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibody (FITC)KLRB1 Reactivity: Rat FACS Host: Mouse Monoclonal 10-78 FITC
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 126-225) antibodyCell Culture Grade KLRB1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2F3 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) antibodyKLRB1 Reactivity: Rat FACS, WB, IP, IHC (fro), RIA Host: Mouse Monoclonal 10-78 unconjugated
anti-Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1) (AA 73-140) antibodyKLRB1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
-
WB 1:300-5000
ELISA 1:500-1000 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 μg/μL
-
Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
Preservative
- ProClin
-
Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
Expiry Date
- 12 months
-
-
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
-
Alternative Name
- CD161
-
Background
-
Synonyms: NKR, CD161, CLEC5B, NKR-P1, NKRP1A, NKR-P1A, hNKR-P1A, Killer cell lectin-like receptor subfamily B member 1, C-type lectin domain family 5 member B, Natural killer cell surface protein P1A, KLRB1
Background: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells.
-
Gene ID
- 3820
-
UniProt
- Q12918
Target
-
