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Bone Morphogenetic Protein 4 (BMP4) antibody

Antigen

Bone Morphogenetic Protein 4 (BMP4)

Synonyms ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, Bmp-4, Bmp2b, Bmp2b1, Bmp2b-1, BOMPR4A, bmp-4, zbmp-4, MGC100779, zgc:100779, BMP4, BMP-4, xbmp4, XBMP-4, Bmp4, MGC127497, zyme, bmp2b, bmp2b1, bmp4
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human, Rat (Rattus), Mouse (Murine)

Application
Alternatives Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS), Immunofluorescence (IF)
Catalog no. ABIN685642
Quantity 100 µg  (1mg/1ml)
Price 255.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 5 to 7 Business Days

Additional Information

Alternative name BMP4
Immunogen Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human BMP4 C-terminus
Format Lyophilized
Reconstitution Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)
Isotype IgG  (Matching secondary antibodies)
Description Synonym: BMP 4, BMP2B, BMP2B1, Bone morphogenetic protein 4, DVR4, ZYME.
Molecular Weight 45kDa
Comments

BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name

BMPs initiate

promote and regulate bone development

growth

remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B)

suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Application Details

Application Notes WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)
Concentration 1mg/1ml
Purification affinity purified by Protein A
Buffer 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
Storage Ship at room temperature. Store at -20°C
Research Area Organogenesis, Growth Factors, Angiogenesis, Signaling
Restrictions For Research Use only

Alternatives

Alternatives for antigen "Bone Morphogenetic Protein 4 (BMP4)", type "Antibodies"
Hosts Rabbit (35), Mouse (22)
Reactivities Human (50), Mouse (Murine) (24), Rat (Rattus) (20), Chicken (3), Rabbit (2), Cow (Bovine) (1), Dog (Canine) (1), Pig (Porcine) (1), Xenopus laevis (1)
Applications Western Blotting (WB) (33), Flow Cytometry (FACS) (18), Immunofluorescence (IF) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (18), ELISA (15), Enzyme Immunoassay (EIA) (3), Immunocytochemistry (ICC) (3), Immunohistochemistry (IHC) (3), Immunoprecipitation (IP) (2), Neutralization (Neut) (2), Blocking Antibody (Inhibition) (1), Functional Studies (Func) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes N-Term (1)